| # | Player | Pos | Team | Rush Efficiency | SF Value |
|---|---|---|---|---|---|
| 1 | Javonte Williams | RB | DAL | 3.2 | 2,046 |
| 2 | James Cook | RB | BUF | 3.2 | 4,831 |
| 3 | Rico Dowdle | RB | PIT | 3.3 | 665 |
| 4 | Derrick Henry | RB | BAL | 3.3 | 1,569 |
| 5 | Kyren Williams | RB | LAR | 3.3 | 2,447 |
| 6 | Chris Rodriguez | RB | JAX | 3.3 | 143 |
| 7 | Blake Corum | RB | LAR | 3.5 | 724 |
| 8 | J.K. Dobbins | RB | DEN | 3.5 | 422 |
| 9 | Jonathan Taylor | RB | IND | 3.5 | 5,065 |
| 10 | Jacory Croskey-Merritt | RB | WAS | 3.5 | 348 |
| 11 | TreVeyon Henderson | RB | NE | 3.5 | 3,358 |
| 12 | Nick Chubb | RB | FA | 3.5 | 32 |
| 13 | Kyle Monangai | RB | CHI | 3.5 | 851 |
| 14 | Rhamondre Stevenson | RB | NE | 3.5 | 384 |
| 15 | David Montgomery | RB | HOU | 3.5 | 870 |
| 16 | Kareem Hunt | RB | FA | 3.6 | 54 |
| 17 | Chase Brown | RB | CIN | 3.6 | 2,965 |
| 18 | Rachaad White | RB | WAS | 3.6 | 313 |
| 19 | De'Von Achane | RB | MIA | 3.6 | 5,858 |
| 20 | D'Andre Swift | RB | CHI | 3.7 | 975 |
| 21 | Jordan Mason | RB | MIN | 3.7 | 165 |
| 22 | Jaylen Warren | RB | PIT | 3.7 | 731 |
| 23 | Tony Pollard | RB | TEN | 3.7 | 295 |
| 24 | Cam Skattebo | RB | NYG | 3.7 | 2,231 |
| 25 | Chuba Hubbard | RB | CAR | 3.7 | 571 |